Comparison of Sublingual and Vaginal Routes of Misoprostol in Termination of First Trimester Missed Abortion
نویسندگان
چکیده
Aim: To compare the sublingual and vaginal routes of misoprostol in termination of first trimester missed abortion. Methodology: The study was carried out in the Obstetrics & Gynecology unit-II of Bahawal Victoria Hospital Bahawalpur, Pakistan, having yearly turnover > 3000 indoor patients. Results: In vaginal misoprostol group 66.7% cases completely aborted while in sublingual group 73.3% expelled successfully (P=.831). In cases with gestational age upto 9 weeks complete abortion was seen 95%, mean insertion to abortion interval for vaginal and sublingual groups were 13.55 and 13.1 hours respectively (P<0.678). Side effects profile was low especially in cases of vaginal group. Conclusion: Vaginal and sublingual misoprostol were found to have same success rate but former was found to have low side effect profile.
منابع مشابه
Comparison of Efficacy and Side Effects of Different Administration Routes of Misoprostol (Oral, Vaginal, and Sublingual) for Second-Trimester Abortion
Background The current study was designed to compare the effectiveness and side effects of oral, vaginal, and sublingual misoprostol in termination of second-trimester pregnancy. Materials and Methods: In this clinical trial (2014 to 2015), 85 pregnant women in the second trimester of pregnancy were included in Imam Reza hospital, Kermanshah, Iran. They were randomly divided into three groups a...
متن کاملComparison between Sublingual and Vaginal Route of Misoprostol in Management of First Trimester Miscarriage Missing
BACKGROUND Each year, more than forty million abortions are occurred whole of the world. Misoprostol is a prostaglandin analogue with a strong uterotonic effect. The present study aimed to compare the efficacy of Misoprostol in first trimester abortion through two sublingual and vaginal routes of administration. METHODS This randomized clinical trial was conducted on 52 consecutive women in f...
متن کاملEfficacy of vaginal misoprostol and vaginal washing with 3% acetic acid for first trimester pregnancy termination: A randomized single blind clinical trial
Introduction: This study was conducted to evaluate the efficacy of 800µg vaginal misoprostol after wetting alkaline PH vagina with 3% acetic acid in comparison with 800µg vaginal misoprostol alone in the alkaline PH vagina in terminating first trimester pregnancies. Methods: In this clinical trial, a total of 100 healthy women between 20 and 40 years old requesting legal terminat...
متن کاملMisoprostol Alone or in Combination with Methotrexate for Termination of Pregnancy at First Trimester
Abortion is an important problem in obstetrics throughout the world. The common and standard method for pregnancy termination at first trimester is surgery (curettage). Nowadays, an effective method of pregnancy termination at first trimester is medical treatments. The aim of this study is to compare misoprostol alone or in combination with methotrexate for pregnancy termination at first trimes...
متن کاملMisoprostol Alone or in Combination with Methotrexate for Termination of Pregnancy at First Trimester
Abortion is an important problem in obstetrics throughout the world. The common and standard method for pregnancy termination at first trimester is surgery (curettage). Nowadays, an effective method of pregnancy termination at first trimester is medical treatments. The aim of this study is to compare misoprostol alone or in combination with methotrexate for pregnancy termination at first trimes...
متن کامل